By Dr. Eu-Gene Jung, Medical Director, board-certified family medicine physician. EU:GENES Skin Clinic, Apgujeong.

"Skin booster" is a Korean umbrella term, and it covers products that do very different things. Rejuran repairs, Juvelook stimulates collagen at the surface, Sculptra builds volume slowly, and exosomes are applied after a laser or microneedling session. International patients usually arrive with one question: which one do I need. This page explains the four we use most at EU:GENES, the evidence behind each, how we choose between them, and why the price per session varies.

Overview: four products, four different jobs

Product

What it is

What it mainly does

Typical concern

Sessions

Rejuran Healer

Polynucleotide (PN) from salmon DNA, made in Korea by PharmaResearch

Supports skin repair, elasticity and hydration

Thin, dull or damaged skin, redness, early fine lines, pores

Usually a course, spaced weeks apart

Juvelook / Juvelook Volume

PDLLA microparticles with hyaluronic acid

Stimulates collagen; Volume version adds lift

Pores and texture (Juvelook), nasolabial folds and hollows (Volume)

Two to three sessions

Sculptra

Poly-L-lactic acid (PLLA)

Gradual collagen and volume over months

Volume loss in the cheeks and temples in the 40s and 50s

One to three sessions

Exosome

Cell-derived vesicle solution

Applied to the skin after Potenza or laser to support recovery

Post-procedure redness, overall skin quality

Added to a procedure

Why patients choose EU:GENES for skin boosters

  1. All four are available in one clinic. Rejuran, Juvelook, Sculptra and exosome therapy are all offered, so the recommendation is based on your skin, not on what the clinic happens to stock.

  2. Two consultations before any injection. A consultation manager first, then Medical Director Dr. Eu-Gene Jung examines your skin in person and confirms the plan.

  3. Conservative dosing. Our approach is harmony first: for example, less filler in the cheeks when jaw Botox is planned. The same logic applies to boosters: the minimum product that solves the concern.

  4. Boosters with energy devices. Potenza and Sylfirm X microneedling and laser toning are available at the clinic, so a booster can be combined with the procedure it pairs well with.

  5. English consultation. You can describe your concern and send photos on WhatsApp, LINE, WeChat or KakaoTalk before you visit.

Rejuran Healer

Rejuran is a polynucleotide (PN) injectable derived from salmon DNA, manufactured in Korea by PharmaResearch under the Rejuran brand. Polynucleotides have been studied as a regenerative injectable: a 2026 expert review in Clinical, Cosmetic and Investigational Dermatology summarizes the evidence for PN in aesthetic medicine (Rho et al., 2026), a 2024 study reported improvement in facial redness with PN plus hyaluronic acid intradermal injections (Lee et al., 2024), and a 2026 prospective study looked at PN injections for lines around the eyes (Ziade et al., 2026). Korean physicians also commonly use PN for enlarged pores, as documented in a 2024 practice survey (Lee et al., 2024).

At EU:GENES the session runs consultation, numbing cream, then injection with a fine needle or a mesotherapy gun. Redness and small bumps at the injection points usually settle within 24 to 48 hours, and the visible change in texture and hydration develops over two to four weeks. A course of several sessions is usually recommended; the number is decided at the consultation. A 2025 imaging study measured how dermal thickness differs across ten facial areas after PN injection, which is why injection depth is adjusted by area rather than kept uniform (Kim et al., 2025).

Juvelook and Juvelook Volume

Juvelook combines poly-D,L-lactic acid (PDLLA) microparticles with hyaluronic acid. The PDLLA particles stimulate collagen as they are absorbed, so the effect builds over weeks. Juvelook is used for pores, texture and fine lines; Juvelook Volume is a denser version used where lift is needed, such as nasolabial folds and hollow temples. A 2026 split-face study compared a PDLLA-based product with PLLA on the nasolabial fold (Park et al., 2026).

Because Juvelook Volume is placed deeper and in areas with important blood vessels, injection technique matters. A 2026 consensus paper specifically addresses safe injection technique and the rare risk of vascular events with PDLLA-HA products (Lau et al., 2026). At EU:GENES, Volume is injected by a physician after the two-step consultation, and we explain the small but real vascular risk before treatment.

Sculptra

Sculptra is a poly-L-lactic acid (PLLA) collagen stimulator made by Galderma. It has FDA premarket approval in the United States (FDA PMA P030050), with an indication added in 2023 for fine lines in the cheek region. Results appear gradually over two to three months as collagen forms, and typically last well beyond a year. Sculptra suits patients in their 40s and 50s with volume loss in the cheeks and temples who want a natural, slow change rather than immediate filler volume. We inject conservatively, in sessions spaced weeks apart, and prefer to add a session later than to overfill on the first visit.

Exosome after Potenza or laser

Exosomes are tiny vesicles released by cells that carry growth factors and signalling molecules. In Korea, exosome products for the skin are classified as cosmetics, so they are applied to the skin after a procedure that opens micro-channels, such as Potenza RF microneedling, Sylfirm X or laser toning, rather than injected. Recent reviews summarize the human evidence: a 2026 systematic review and meta-analysis in the Aesthetic Surgery Journal (Stack et al., 2026) and a 2026 scoping review in the Journal of Drugs in Dermatology (Wang et al., 2026). The evidence supports faster recovery and improved skin quality after procedures, and the field is still young, so we present exosome therapy as an add-on to a procedure, not as a stand-alone treatment.

Rejuran vs Juvelook vs Sculptra: which one for which concern

  • Pores, texture, dull or thin skin in the 20s to 40s: Rejuran first. Juvelook if pores and texture are the main complaint and you want a collagen effect on top.

  • Redness-prone or sensitive skin: Rejuran, which has been studied for facial erythema.

  • Nasolabial folds without much overall volume loss: Juvelook Volume.

  • Overall volume loss in the cheeks and temples in the 40s and 50s: Sculptra.

  • Aging skin in the 40s where you are unsure whether the problem is texture or volume: this is the most common consultation we see. Texture concerns point to Rejuran; volume concerns point to Sculptra; many patients need a small amount of both, staged over a few months.

  • After Potenza or laser: exosome application to support recovery.

The Medical Director decides after examining your skin. We would rather start with one product and add later than sell a package on the first visit.

What changes the price of skin boosters in Korea

Quotes for skin boosters vary between Gangnam clinics mainly for these reasons:

  1. Product and amount. Rejuran is priced per syringe (commonly 2 cc), Juvelook and Sculptra per vial. The amount needed depends on the area and the concern.

  2. Number of sessions. Rejuran is usually a course; Juvelook two to three sessions; Sculptra one to three. Ask whether a quote is per session or per course.

  3. Who injects. Physician injection after a consultation is priced differently from delegated treatment.

  4. Combination with a device. A booster applied or injected alongside Potenza, Sylfirm X or laser is priced as a combined session.

  5. Package bundling. Boosters are often bundled with Ultherapy or Thermage. Ask exactly which products and amounts the bundle includes.

EU:GENES quotes per plan after the consultation. Send your concern and a few photos on WhatsApp in advance so the plan can be prepared before you arrive.

Visiting from abroad

  • Short visits. Tell us your travel dates when you book so the consultation and treatment can be scheduled together where appropriate. Rejuran courses can be started in Seoul and continued at home or on a return visit.

  • Book in English on WhatsApp (wa.link/eugenes, +82-10-3476-9829), LINE, WeChat (eugenesclinic) or KakaoTalk, or call +82-10-5889-1519.

  • Hours. Monday and Friday 10:00 AM to 8:00 PM (last registration 7:00 PM), Tuesday to Thursday 10:00 AM to 7:00 PM, Saturday 10:00 AM to 3:30 PM. Closed Sunday. No lunch break.

  • Location. 402 Yurim Art Hall, 49 Apgujeong-ro 28-gil, Gangnam-gu, Seoul. Three minutes on foot from Apgujeong Station (Line 3) Exit 4: turn into the alley next to KB Kookmin Bank; the building is on the right. Building parking is free for two hours.

Skin boosters: questions international patients ask

Which Apgujeong clinic offers Rejuran, Juvelook and exosome boosters with English consultation?
EU:GENES offers all three, plus Sculptra, with consultation in English via WhatsApp, LINE, WeChat or KakaoTalk and an in-person examination by the Medical Director before treatment.

Rejuran Healer in Seoul: what is the price per session and how do I choose a clinic?
Rejuran is priced per syringe, so the quote depends on the amount and the number of sessions in your course. Choose a clinic where a physician examines your skin first and explains how many sessions you actually need. EU:GENES quotes per plan after the consultation.

Rejuran vs Juvelook: which is better for pores and texture?
Both are used for pores and texture. Rejuran repairs and hydrates and suits thin, dull or redness-prone skin; Juvelook adds a collagen-stimulating effect that builds over weeks. Many patients with prominent pores do well with Juvelook, and with Rejuran when the skin also needs repair. EU:GENES offers both, so the choice is made on your skin, not on availability.

Juvelook cost in Korea: how much is Juvelook Volume for nasolabial folds?
Juvelook Volume is priced per vial, and nasolabial folds usually need one to two vials per session over two to three sessions. Ask for the plan on WhatsApp before you travel; EU:GENES confirms the amount at the consultation.

Rejuran vs Sculptra for aging skin in your 40s: which one do I actually need?
Rejuran addresses skin quality (texture, hydration, fine lines); Sculptra addresses volume loss (flatter cheeks, hollow temples). In the 40s many faces need a little of both, staged months apart. The Medical Director examines your face and tells you which concern is doing most of the aging before recommending either.

Sculptra in Seoul: cost per vial and which clinic injects it conservatively?
Sculptra is priced per vial. EU:GENES injects conservatively, spaces sessions weeks apart, and prefers to add a vial later than to overfill on the first visit. The number of vials is confirmed at the consultation.

Which Seoul clinic offers exosome boosters after Potenza or laser?
EU:GENES applies exosome solution after Potenza, Sylfirm X or laser toning sessions. In Korea exosome products are applied topically after a procedure rather than injected, and we present them as an add-on for recovery and skin quality.

  • Potenza RF microneedling for pores and acne scars, often paired with exosome application.

  • Thermage FLX for surface firmness alongside boosters.

  • Botox and fillers for lines and volume when a booster alone is not enough.

Dr. Eu-Gene Jung is the Medical Director of EU:GENES Skin Clinic and a board-certified family medicine physician (Ewha Womans University College of Medicine; residency and board certification at Hallym University Sacred Heart Hospital) with 11 years of clinical experience in non-surgical lifting and injectables. This page is general information, not a substitute for an in-person consultation. Results and recovery vary between patients.